For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of ramipril in the pediatric population. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ramipril in the elderly.
However, elderly patients are more likely to have age-related heart, kidney, or liver problems, which may require an adjustment in the dose for patients receiving ramipril. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended.
Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:.
In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium salt. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem.
In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and keep it down. Taking it again could be fatal cause death. For people with kidney problems: People with kidney problems may have a higher risk for certain serious side effects from this drug, including high potassium levels.
Tell your doctor if you have kidney problems, heart failure, and one- or two-sided renal artery stenosis. Your doctor will decide if ramipril is right for you. For people with liver problems: Ramipril should be used with caution if you have liver problems. This drug can worsen your liver function and change your electrolyte levels.
For people with low white blood cells: Ramipril can cause low white blood cell counts. This can increase your risk for infections, especially if you have a history of lupus, kidney problems, or scleroderma.
If you have any signs of an infection such as a fever or sore throat , tell your doctor right away. For people with diabetes: This drug can affect your blood sugar levels. Your doctor may need to change your dose of your diabetes drugs. Your doctor will tell you how often to test your blood sugar levels.
For pregnant women: Ramipril is a category D pregnancy drug. That means two things:. Ask your doctor to tell you about the specific harm that may be done to the fetus. For women who are breastfeeding: Ramipril may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.
For seniors: Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. Rampiril can interact with several other medications. Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.
Below is a list of medications that can interact with rampiril. This list does not contain all drugs that may interact with rampiril. Before taking rampiril, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use.
Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. These supplements may increase your blood potassium when taken with ramipril. These supplements include:.
These medications may increase your blood potassium when taken with ramipril. These drugs include:. Ramipril can increase the levels of lithium in your body. This means that you may have more side effects. When taken with ramipril, certain joint pain drugs can cause side effects. These include reddening and warming of your face flushing , nausea, vomiting, and low blood pressure. Patients: One hundred fifty-nine patients with mild to moderate essential hypertension were enrolled.
Two patients were excluded from the efficacy analysis because they failed to return for follow-up. Interventions: Patients were randomized to receive ramipril 2. Ramipril is a lipophilic angiotensin-converting enzyme inhibitor suitable for once-daily administration. In addition to decreasing angiotensin II and increasing bradykinin levels, ramipril increases the levels of vasodilatory renal medullary neutral lipids and inhibits platelet-derived growth factor-induced proliferation of glomerulus cells.
Ramipril also decreases transforming growth factor-beta in the kidney.
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